Conservative therapies for hemorrhagic radiation proctitis: a review

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Conservative therapies for hemorrhagic radiation proctitis: a review.

Chronic radiation proctitis represents a challenging condition seen with increased frequency due to the common use of radiation for treatment of pelvic cancer. Hemorrhagic radiation proctitis represents the most feared complication of chronic radiation proctitis. There is no consensus for the management of this condition despite the great number of clinical approaches and techniques that have b...

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Formalin Application for the Treatment of Radiation-Induced Hemorrhagic Proctitis

Radiation-induced hemorrhagic proctitis (RIHP) is a serious complication of pelvic irradiation, and a 4% formalin solution has been used for 20 years in treating this sequelae. The first case involving formalin application for treatment of RIHP in Korea was reported in 1996, but there are no additional studies beyond this date. Our study reviews the use of formalin instillation and selective ap...

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A rat model for radiation-induced proctitis.

Radiation proctitis is a frequent acute complication encountered with pelvic irradiation. This study was aimed at establishing the optimal radiation dose for radiation-induced proctitis in rats. Female Wistar rats were used. The rectal specimens were examined morphologically at 5th and 10th day following 10-30 Gy irradiation in single fraction. With increasing dose, mucosal damage became worse,...

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Application of 10 percent formalin for the treatment of radiation-induced hemorrhagic proctitis.

PURPOSE Rectal instillation of 4 percent formalin solution has been described as a successful treatment for hemorrhagic radiation proctitis recalcitrant to medical treatment. We present our experience with a new method of treatment involving the topical application of 10 percent buffered formalin, which is well tolerated and suitable for office use. METHODS Patients with marked or refractory ...

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Efficacy and safety of argon plasma coagulation for the treatment of hemorrhagic radiation proctitis.

OBJECTIVE To evaluate the efficacy, safety and medium-/long-term clinical course of patients undergoing endoscopic treatment with argon plasma coagulation for hemorrhagic radiation proctopathy. DESIGN Descriptive, retrospective study with medium- and long-term follow-up. PATIENTS, MATERIAL AND METHODS Ten patients were treated with argon plasma coagulation for hemorrhagic radiation proctopa...

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ژورنال

عنوان ژورنال: Revista do Hospital das Clínicas

سال: 2003

ISSN: 0041-8781

DOI: 10.1590/s0041-87812003000500008